Ontology highlight
ABSTRACT:
SUBMITTER: Coulton A
PROVIDER: S-EPMC7029859 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Coulton Alexander A Przewieslik-Allen Alexandra M AM Burridge Amanda J AJ Shaw Daniel S DS Edwards Keith J KJ Barker Gary L A GLA
PloS one 20200219 2
Segregation distortion is the phenomenon in which genotypes deviate from expected Mendelian ratios in the progeny of a cross between two varieties or species. There is not currently a widely used consensus for the appropriate statistical test, or more specifically the multiple testing correction procedure, used to detect segregation distortion for high-density single-nucleotide polymorphism (SNP) data. Here we examine the efficacy of various multiple testing procedures, including chi-square test ...[more]