Ontology highlight
ABSTRACT:
SUBMITTER: Qin Z
PROVIDER: S-EPMC7030199 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Qin Zhao Z Yiran Ao A Kai Yang Y Xiaoli Su S Xiaoqiang Lü L
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20170201 1
<h4>Objective</h4>This study investigated the effect of clock gene PER1 on the expression levels of other clock genes in clock gene networks in oral squamous cell carcinoma cells.<h4>Methods</h4>We used RNA interference mediated by short hairpin RNAs (shRNAs) to effectively knock down PER1 in SCC15 human oral squamous cell carcinoma cells. Flow cytometry was used to detect the degree of proliferation and apoptosis of the cells after PER1 knockdown, and quantitative real-time PCR was used to dete ...[more]