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Zombi: a phylogenetic simulator of trees, genomes and sequences that accounts for dead linages.


ABSTRACT: SUMMARY:Here we present Zombi, a tool to simulate the evolution of species, genomes and sequences in silico, that considers for the first time the evolution of genomes in extinct lineages. It also incorporates various features that have not to date been combined in a single simulator, such as the possibility of generating species trees with a pre-defined variation of speciation and extinction rates through time, simulating explicitly intergenic sequences of variable length and outputting gene tree-species tree reconciliations. AVAILABILITY AND IMPLEMENTATION:Source code and manual are freely available in https://github.com/AADavin/ZOMBI/. SUPPLEMENTARY INFORMATION:Supplementary data are available at Bioinformatics online.

SUBMITTER: Davin AA 

PROVIDER: S-EPMC7031779 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Zombi: a phylogenetic simulator of trees, genomes and sequences that accounts for dead linages.

Davín Adrián A AA   Tricou Théo T   Tannier Eric E   de Vienne Damien M DM   Szöllősi Gergely J GJ  

Bioinformatics (Oxford, England) 20200201 4


<h4>Summary</h4>Here we present Zombi, a tool to simulate the evolution of species, genomes and sequences in silico, that considers for the first time the evolution of genomes in extinct lineages. It also incorporates various features that have not to date been combined in a single simulator, such as the possibility of generating species trees with a pre-defined variation of speciation and extinction rates through time, simulating explicitly intergenic sequences of variable length and outputting  ...[more]

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