Transcriptome analysis of ankylosed primary molars with infraocclusion.
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ABSTRACT:
SUBMITTER: Tong A
PROVIDER: S-EPMC7033215 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
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Transcriptome analysis of ankylosed primary molars with infraocclusion.
Tong Annie A Chow Yuh-Lit YL Xu Katie K Hardiman Rita R Schneider Paul P Tan Seong-Seng SS
International journal of oral science 20200221 1
Primary molar ankylosis with infraocclusion can retard dental arch development and cause dental asymmetry. Despite its widespread prevalence, little is known about its molecular etiology and pathogenesis. To address this, RNA sequencing was used to generate transcriptomes of furcal bone from infraoccluded (n = 7) and non-infraoccluded (n = 9) primary second molars, all without succeeding biscuspids. Of the 18 529 expressed genes, 432 (2.3%) genes were differentially expressed between the two gro ...[more]
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