Efficacy of prebiotics and probiotics for functional dyspepsia: A systematic review and meta-analysis.

ABSTRACT:

Background

Functional dyspepsia (FD) is a functional gastrointestinal disorder. Evidence suggests that disturbance of the gastrointestinal microbiota may be implicated in FD. We performed a systematic review and meta-analysis to examine the efficacy of prebiotics and probiotics for FD.

Methods

MEDLINE, EMBASE, and the Cochrane Controlled Trials Register were searched (through September 2018). Randomized controlled trials (RCTs) that recruited adults with FD and that compared prebiotics, probiotics, or synbiotics with placebo or no therapy were eligible. Eligibility assessment and data extraction were performed by two independent researchers. Dichotomous symptom data were pooled to obtain a relative risk (RR) with a 95% confidence interval (CI) of remaining symptomatic after

SUBMITTER: Zhang J 

PROVIDER: S-EPMC7035106 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature