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Association of peripheral neutrophil count with intracranial atherosclerotic stenosis.


ABSTRACT: BACKGROUND:Inflammation plays an important role in atherosclerosis but the contribution of neutrophils to this process is unclear. We sought to assess whether neutrophil count is associated with intracranial atherosclerotic stenosis (ICAS). METHODS:A total of 2847 individuals were included in our study, including 1363 with acute ischemic stroke and 1484 normal controls without stroke. The presence of ICAS was confirmed by magnetic resonance angiography. The association between neutrophil count and ICAS was evaluated by multivariable logistic regression analysis. RESULTS:Among 2847 individuals included in this study, individuals with ICAS had higher neutrophil counts than those without ICAS in groups with and without stroke (P?

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7035752 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Association of peripheral neutrophil count with intracranial atherosclerotic stenosis.

Zhang Xing X   Hou Xiao-He XH   Ma Ya-Hui YH   Shen Xue-Ning XN   Cao Xi-Peng XP   Song Jing-Hui JH   Tan Lan L   Yu Jin-Tai JT  

BMC neurology 20200222 1


<h4>Background</h4>Inflammation plays an important role in atherosclerosis but the contribution of neutrophils to this process is unclear. We sought to assess whether neutrophil count is associated with intracranial atherosclerotic stenosis (ICAS).<h4>Methods</h4>A total of 2847 individuals were included in our study, including 1363 with acute ischemic stroke and 1484 normal controls without stroke. The presence of ICAS was confirmed by magnetic resonance angiography. The association between neu  ...[more]

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