Ontology highlight
ABSTRACT:
SUBMITTER: Pinto L
PROVIDER: S-EPMC7036751 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Pinto Lucas L Rajan Kanaka K DePasquale Brian B Thiberge Stephan Y SY Tank David W DW Brody Carlos D CD
Neuron 20190926 4
Neural activity throughout the cortex is correlated with perceptual decisions, but inactivation studies suggest that only a small number of areas are necessary for these behaviors. Here we show that the number of required cortical areas and their dynamics vary across related tasks with different cognitive computations. In a visually guided virtual T-maze task, bilateral inactivation of only a few dorsal cortical regions impaired performance. In contrast, in tasks requiring evidence accumulation ...[more]