Ontology highlight
ABSTRACT:
SUBMITTER: Stankova P
PROVIDER: S-EPMC7036817 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Staňková Pavla P Kučera Otto O Peterová Eva E Lotková Halka H Maseko Tumisang Edward TE Nožičková Kateřina K Červinková Zuzana Z
International journal of molecular sciences 20200207 3
Maladaptation of mitochondrial oxidative flux seems to be a considerable feature of nonalcoholic fatty liver disease (NAFLD). The aim of this work was to induce NAFLD in mice fed a Western-style diet (WD) and to evaluate liver mitochondrial functions. Experiments were performed on male C57BL/6J mice fed with a control diet or a WD for 24 weeks. Histological changes in liver and adipose tissue as well as hepatic expression of fibrotic and inflammatory genes and proteins were evaluated. The mitoch ...[more]