Ontology highlight
ABSTRACT:
SUBMITTER: Batista R
PROVIDER: S-EPMC7037401 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Batista Rui R Lima Luís L Vinagre João J Pinto Vasco V Lyra Joana J Máximo Valdemar V Santos Lúcio L Soares Paula P
International journal of molecular sciences 20200131 3
Telomerase reverse transcriptase gene promoter (<i>TERTp</i>) mutations are recognized as one of the most frequent genetic events in bladder cancer (BC). No studies have focused on the relevance of TERTp mutations in the specific group of tumors treated with Bacillus Calmette-Guérin (BCG) intravesical therapy. Methods - 125 non muscle invasive BC treated with BCG therapy (BCG-NMIBC) were screened for <i>TERTp</i> mutations, <i>TERT</i> rs2853669 single nucleotide polymorphism, and Fibroblast Gro ...[more]