Ontology highlight
ABSTRACT:
SUBMITTER: Tsuji K
PROVIDER: S-EPMC7037711 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Tsuji Kenji K Kitamura Shinji S Wada Jun J
International journal of molecular sciences 20200123 3
Mesenchymal stem cells (MSCs) have immunomodulatory and regenerative effects in many organs, including the kidney. Emerging evidence has shown that the trophic effects from MSCs are mainly mediated by the paracrine mechanism rather than the direct differentiation of MSCs into injured tissues. These secretomes from MSCs include cytokines, growth factors, chemokines and extracellular vesicles (EVs) containing microRNAs, mRNAs, and proteins. Many research studies have revealed that secretomes from ...[more]