The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control.
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ABSTRACT:
SUBMITTER: Manzano-Lopez J
PROVIDER: S-EPMC7038166 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control.
Manzano-López Javier J Monje-Casas Fernando F
International journal of molecular sciences 20200121 3
The Cdc14 phosphatase is a key regulator of mitosis in the budding yeast <i>Saccharomyces cerevisiae</i>. Cdc14 was initially described as playing an essential role in the control of cell cycle progression by promoting mitotic exit on the basis of its capacity to counteract the activity of the cyclin-dependent kinase Cdc28/Cdk1. A compiling body of evidence, however, has later demonstrated that this phosphatase plays other multiple roles in the regulation of mitosis at different cell cycle stage ...[more]
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