Dataset Information

Data-Driven Modeling of Smartphone-Based Electrochemiluminescence Sensor Data Using Artificial Intelligence.

ABSTRACT: Understanding relationships among multimodal data extracted from a smartphone-based electrochemiluminescence (ECL) sensor is crucial for the development of low-cost point-of-care diagnostic devices. In this work, artificial intelligence (AI) algorithms such as random forest (RF) and feedforward neural network (FNN) are used to quantitatively investigate the relationships between the concentration of Ru(bpy)32+ luminophore and its experimentally measured ECL and electrochemical data. A smartphone-based ECL sensor with Ru(bpy)32+/TPrA was developed using disposable screen-printed carbon electrodes. ECL images and amperograms were simultaneously obtained following 1.2-V voltage application. These multimodal data were analyzed by RF and FNN algorithms, which allowed the prediction of Ru(bpy)32+ concentration using multiple key features. High correlation (0.99 and 0.96 for RF and FNN, respectively) between actual and predicted values was achieved in the detection range between 0.02 µM and 2.5 µM. The AI approaches using RF and FNN were capable of directly inferring the concentration of Ru(bpy)32+ using easily observable key features. The results demonstrate that data-driven AI algorithms are effective in analyzing the multimodal ECL sensor data. Therefore, these AI algorithms can be an essential part of the modeling arsenal with successful application in ECL sensor data modeling.

SUBMITTER: Ccopa Rivera E

PROVIDER: S-EPMC7038330 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Data-Driven Modeling of Smartphone-Based Electrochemiluminescence Sensor Data Using Artificial Intelligence.

Ccopa Rivera Elmer E Swerdlow Jonathan J JJ Summerscales Rodney L RL Uppala Padma P Tadi PPT Maciel Filho Rubens R Neto Mabio R C MRC Kwon Hyun J HJ

Sensors (Basel, Switzerland) 20200123 3

Understanding relationships among multimodal data extracted from a smartphone-based electrochemiluminescence (ECL) sensor is crucial for the development of low-cost point-of-care diagnostic devices. In this work, artificial intelligence (AI) algorithms such as random forest (RF) and feedforward neural network (FNN) are used to quantitatively investigate the relationships between the concentration of Ru(bpy)32+ luminophore and its experimentally measured ECL and electrochemical data. A smartphone ...[more]

PMID: 31979213

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Dataset Information

Data-Driven Modeling of Smartphone-Based Electrochemiluminescence Sensor Data Using Artificial Intelligence.

Publications

Data-Driven Modeling of Smartphone-Based Electrochemiluminescence Sensor Data Using Artificial Intelligence.

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