Unknown

Dataset Information

0

Distribution characteristics of cow's milk-sIgE components in children with respiratory allergic diseases in southern China.

ABSTRACT: BACKGROUND:Cow's milk (CM) is the main food allergen for toddlers and infants. Presently, studies on CM specific immunoglobulin E (sIgE) sensitization and positive distribution of CM components ALA-, CAS-, and BLG-sIgE are lacking in infants with respiratory allergic diseases, especially in southern China. This study therefore aimed to investigate the distribution of CM sensitization and the relation between its components ?-lactalbumin (ALA), ?-lactoglobulin (BLG) and casein (CAS) sIgE in children with respiratory allergic diseases in southern China. METHODS:A total of 1839 children (?12?years) with respiratory diseases and detected CM-sIgE levels were included. Serum samples were collected from the Respiratory Diseases Bioresources Center of the National Center for Respiratory Diseases in southern China from August 2012 to July 2017. ALA-, BLG-, and CAS-sIgE were detected and questionnaires were completed in 103 children. RESULTS:A total of 36.7% children were positive for CM-sIgE. CM-sIgE levels were higher in asthmatic bronchitis (AB) group than in other allergic respiratory disease groups (all P?

SUBMITTER: Huang H 

PROVIDER: S-EPMC7038540 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Distribution characteristics of cow's milk-sIgE components in children with respiratory allergic diseases in southern China.

Huang Huimin H   Luo Wenting W   Wei Nili N   Liang Xueqing X   Zheng Peiyan P   Hu Haisheng H   Sun Baoqing B  

BMC pediatrics 20200224 1

<h4>Background</h4>Cow's milk (CM) is the main food allergen for toddlers and infants. Presently, studies on CM specific immunoglobulin E (sIgE) sensitization and positive distribution of CM components ALA-, CAS-, and BLG-sIgE are lacking in infants with respiratory allergic diseases, especially in southern China. This study therefore aimed to investigate the distribution of CM sensitization and the relation between its components α-lactalbumin (ALA), β-lactoglobulin (BLG) and casein (CAS) sIgE  ...[more]

Similar Datasets

Unknown Butter Tolerance in Children Allergic to Cow's Milk.
| S-EPMC4341340 | biostudies-other
Unknown Higher Polygenetic Predisposition for Asthma in Cow's Milk Allergic Children.
| S-EPMC6266812 | biostudies-other
Unknown Genetic susceptibility for cow's milk allergy in Dutch children: the start of the allergic march?
| S-EPMC4776421 | biostudies-literature
Unknown Mineral Intake and Status of Cow's Milk Allergic Infants Consuming an Amino Acid-based Formula.
| S-EPMC5559186 | biostudies-literature
Unknown Direct Inhibition of the Allergic Effector Response by Raw Cow's Milk-An Extensive In Vitro Assessment.
| S-EPMC7290799 | biostudies-literature
Unknown Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cow's Milk Allergy.
| S-EPMC8400770 | biostudies-literature
Unknown Cow's milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT.
| S-EPMC4769487 | biostudies-literature
Unknown Mesenteric IL-10-producing CD5+ regulatory B cells suppress cow's milk casein-induced allergic responses in mice.
| S-EPMC4726293 | biostudies-literature
Unknown Zinc binding in cow's milk and human milk.
| S-EPMC1154118 | biostudies-other
Unknown Excretion of Dietary Cow's Milk Derived Peptides Into Breast Milk.
| S-EPMC6424006 | biostudies-literature