Browse
Submit Data
Databases
API
Help

Dataset Information

24 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.

ABSTRACT: Localized surface plasmon resonances (LSPRs) in heavily doped copper chalcogenides are unique because LSPR energy can be adjusted by adjusting doping or stoichiometry. However, there are few investigations on the LSPRs of bimetal copper-based chalcogenides. Herein, bimetal Cu5FeS4 (CFS) nanoparticles were synthesized by a facile hot injection of a molecular precursor. The tunable plasmon resonance absorption of CFS nanoparticles is achieved by the decrease of the ratio of copper to iron and the treatment of n-dodecylphosphoric acid (DDPA). After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. Our work provides insight into bimetal copper-based chalcogenides to achieve tunable LSPRs, which opens up the possibility of rationally designing plasmonic bimetal copper-based chalcogenides.

SUBMITTER: Yuan L

PROVIDER: S-EPMC7039924 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Probing dynamically tunable localized surface plasmon resonances of film-coupled nanoparticles by evanescent wave excitation.

Project description:The localized surface plasmon resonance (LSPR) spectrum associated with a gold nanoparticle (NP) coupled to a gold film exhibits extreme sensitivity to the nanogap region where the fields are tightly localized. The LSPR of an ensemble of film-coupled NPs can be observed using an illumination scheme similar to that used to excite the surface plasmon resonance (SPR) of a thin metallic film; however, in the present system, the light is used to probe the highly sensitive distance-dependent LSPR of the gaps between NPs and film rather than the delocalized SPR of the film. We show that the SPR and LSPR spectral contributions can be readily distinguished, and we compare the sensitivities of both modes to displacements in the average gap between a collection of NPs and the gold film. The distance by which the NPs are suspended in solution above the gold film is fixed via a thin molecular spacer layer and can be further modulated by subjecting the NPs to a quasistatic electric field. The observed LSPR spectral shifts triggered by the applied voltage can be correlated with angstrom scale displacements of the NPs, suggesting the potential for chip-scale or flow-cell plasmonic nanoruler devices with extreme sensitivity.

| S-EPMC3324644 | biostudies-literature

Tunable Dipole Surface Plasmon Resonances of Silver Nanoparticles by Cladding Dielectric Layers.

Project description:The tunability of surface plasmon resonance can enable the highest degree of localised surface plasmon enhancement to be achieved, based on the emitting or absorbing wavelength. In this article, tunable dipole surface plasmon resonances of Ag nanoparticles (NPs) are realized by modification of the SiO2 dielectric layer thicknesses. SiO2 layers both beneath and over the Ag NPs affected the resonance wavelengths of local surface plasmons (LSPs). By adjusting the SiO2 thickness beneath the Ag NPs from 5 nm to 20 nm, the dipole surface plasmon resonances shifted from 470 nm to 410 nm. Meanwhile, after sandwiching the Ag NPs by growing SiO2 before NPs fabrication and then overcoating the NPs with various SiO2 thicknesses from 5 nm to 20 nm, the dipole surface plasmon resonances changed from 450 nm to 490 nm. The SiO2 cladding dielectric layer can tune the Ag NP surface charge, leading to a change in the effective permittivity of the surrounding medium, and thus to a blueshift or redshift of the resonance wavelength. Also, the quadrupole plasmon resonances were suppressed by the SiO2 cladding layer because the dielectric SiO2 can suppress level splitting of surface plasmon resonances caused by the Ag NP coupling effect.

| S-EPMC4517390 | biostudies-other

CuGeO<sub>3</sub> Nanoparticles: An Efficient Photothermal Theragnosis Agent for CT Imaging-Guided Photothermal Therapy of Cancers.

Project description:The photothermal agents have been widely developed due to the minimally invasive treatment for targeted tumor photothermal therapy, which is considered to have great potential for antitumor bioapplications. The development of multifunctional photothermal agents is extremely challenging. This work presents a novel photothermal theragnosis agent, i.e., CuGeO3 nanoparticles (CGO NPs), showing intense absorption in the near-infrared (NIR) window and excellent ability of CT imaging. Due to the strong NIR absorption, CGO NPs exhibit excellent photothermal effect with a photothermal conversion efficiency of 59.4%. Moreover, because of the high X-ray attenuation coefficient of germanium, the CGO NPs have a great potential of CT imaging diagnosis in clinical application. Additionally, the CGO NPs show negligible cytotoxicity in vitro and in vivo, indicating that it can be served as an outstanding contrast and anticancer agent in a biosafe way. Our work opens the way for the development of bimetallic copper-based oxides used in photothermal diagnostic agents for cancer treatment.

| S-EPMC7717952 | biostudies-literature

MEMS Tunable Metasurfaces Based on Gap Plasmon or Fabry-Perot Resonances.

Project description:Tunable metasurfaces promise to enable adaptive optical systems with complex functionalities. Among possible realizations, a recent platform combining microelectromechanical systems (MEMS) with gap-surface plasmon (GSP) metasurfaces offers high modulation efficiency, broadband operation, and fast response. We compare tunable metasurfaces operating in GSP and Fabry-Pérot (FP) regions by investigating polarization-independent blazed gratings both numerically and experimentally. Peak efficiency is calculated to be ∼75% in both cases (∼40% in measurements), while the operation bandwidth is found larger when operating in the GSP region. Advantages of operating in the FP region include relaxed assembly requirements and operation tolerances. Additionally, simulation and experimental results show that coupling between neighboring unit cells increases for larger air gaps, resulting in deteriorated efficiency. We believe the presented analysis provides important guidelines for designing tunable metasurfaces for diverse applications in miniaturized adaptive optical systems.

| S-EPMC9479152 | biostudies-literature

Simulating Plasmon Resonances of Gold Nanoparticles with Bipyramidal Shapes by Boundary Element Methods.

Project description:Computational modeling and accurate simulations of localized surface plasmon resonance (LSPR) absorption properties are reported for gold nanobipyramids (GNBs), a class of metal nanoparticle that features highly tunable, geometry-dependent optical properties. GNB bicone models with spherical tips performed best in reproducing experimental LSPR spectra while the comparison with other geometrical models provided a fundamental understanding of base shapes and tip effects on the optical properties of GNBs. Our results demonstrated the importance of averaging all geometrical parameters determined from transmission electron microscopy images to build representative models of GNBs. By assessing the performances of LSPR absorption spectra simulations based on a quasi-static approximation, we provided an applicability range of this approach as a function of the nanoparticle size, paving the way to the theoretical study of the coupling between molecular electron densities and metal nanoparticles in GNB-based nanohybrid systems, with potential applications in the design of nanomaterials for bioimaging, optics and photocatalysis.

| S-EPMC7584360 | biostudies-literature

Self-Assembled CuCo2S4 Nanoparticles for Efficient Chemo-Photothermal Therapy of Arterial Inflammation.

Project description:Cardiovascular disease caused by atherosclerosis (AS) seriously affects human health. Photothermal therapy (PTT) brings hope to the diagnosis and treatment of AS, with the development of nanotechnology. To improve treatment efficiency, self-assembled CuCo2S4 nanocrystals (NCs) were developed as a drug-delivery nanocarrier, triggered by near-infrared (NIR) light for efficient chemophotothermal therapy of arterial inflammation. The as-prepared self-assembled CuCo2S4 NCs exhibited excellent biocompatibility and a very high chloroquine (CL)-loading content. In addition, the self-assembled CuCo2S4 NCs/CL nanocomposites showed good photothermal performance, due to strong absorption in the NIR region, and the release of CL from the NCs/CL nanocomposites was driven by NIR light. When illuminated by NIR light, both PTT from the NCs and chemotherapy from the CL were simultaneously triggered, resulting in killing macrophages with a synergistic effect. Moreover, chemo-photothermal therapy with CuCo2S4 NCs/CL nanocomposites showed an effective therapeutic effect for arterial inflammation, in vivo. Our work demonstrated that chemo-photothermal therapy could be a promising strategy for the treatment of arterial inflammation against atherosclerosis.

| S-EPMC9737671 | biostudies-literature

Dual Plasmon Resonances and Tunable Electric Field in Structure-Adjustable Au Nanoflowers for Improved SERS and Photocatalysis.

Project description:Flower-like metallic nanocrystals have shown great potential in the fields of nanophononics and energy conversion owing to their unique optical properties and particular structures. Herein, colloid Au nanoflowers with different numbers of petals were prepared by a steerable template process. The structure-adjustable Au nanoflowers possessed double plasmon resonances, tunable electric fields, and greatly enhanced SERS and photocatalytic activity. In the extinction spectra, Au nanoflowers had a strong electric dipole resonance located around 530 to 550 nm. Meanwhile, a longitudinal plasmon resonance (730~760 nm) was obtained when the number of petals of Au nanoflowers increased to two or more. Numerical simulations verified that the strong electric fields of Au nanoflowers were located at the interface between the Au nanosphere and Au nanopetals, caused by the strong plasmon coupling. They could be further tuned by adding more Au nanopetals. Meanwhile, much stronger electric fields of Au nanoflowers with two or more petals were identified under longitudinal plasmon excitation. With these characteristics, Au nanoflowers showed excellent SERS and photocatalytic performances, which were highly dependent on the number of petals. Four-petal Au nanoflowers possessed the highest SERS activity on detecting Rhodamine B (excited both at 532 and 785 nm) and the strongest photocatalytic activity toward photodegrading methylene blue under visible light irradiation, caused by the strong multi-interfacial plasmon coupling and longitudinal plasmon resonance.

| S-EPMC8466837 | biostudies-literature

Scalable Synthesis of Biodegradable Black Mesoporous Silicon Nanoparticles for Highly Efficient Photothermal Therapy.

Project description:Porous silicon (PSi) has attracted wide interest as a potential material for various fields of nanomedicine. However, until now, the application of PSi in photothermal therapy has not been successful due to its low photothermal conversion efficiency. In the present study, biodegradable black PSi (BPSi) nanoparticles were designed and prepared via a high-yield and simple reaction. The PSi nanoparticles possessed a low band gap of 1.34 eV, a high extinction coefficient of 13.2 L/g/cm at 808 nm, a high photothermal conversion efficiency of 33.6%, good photostability, and a large surface area. The nanoparticles had not only excellent photothermal properties surpassing most of the present inorganic photothermal conversion agents (PCAs) but they also displayed good biodegradability, a common problem encountered with the inorganic PCAs. The functionality of the BPSi nanoparticles in photothermal therapy was verified in tumor-bearing mice in vivo. These results showed clearly that the photothermal treatment was highly efficient to inhibit tumor growth. The designed PCA material of BPSi is robust, easy to prepare, biocompatible, and therapeutically extremely efficient and it can be integrated with several other functionalities on the basis of simple silicon chemistry.

| S-EPMC6150643 | biostudies-literature

Multipole plasmon resonances in gold nanorods.

Project description:The optical properties of gold rods electrochemically deposited in anodic aluminum oxide templates have been investigated. Homogeneous suspensions of rods with an average diameter of 85 nm and varying lengths of 96, 186, 321, 465, 495, 578, 641, 735, and 1175 nm were fabricated. The purity and dimensions of these rod nanostructures allowed us to observe higher-order multipole resonances for the first time in a colloidal suspension. The experimental optical spectra agree with discrete dipole approximation calculations that have been modeled from the dimensions of the gold nanorods.

| S-EPMC3241533 | biostudies-literature

Thermally Stable Magneto-Plasmonic Nanoparticles for SERS with Tunable Plasmon Resonance.

Project description:Bifunctional magneto-plasmonic nanoparticles that exhibit synergistically magnetic and plasmonic properties are advanced substrates for surface-enhanced Raman spectroscopy (SERS) because of their excellent controllability and improved detection potentiality. In this study, composite magneto-plasmonic nanoparticles (Fe3O4@AgNPs) were formed by mixing colloid solutions of 50 nm-sized magnetite nanoparticles with 13 nm-sized silver nanoparticles. After drying of the layer of composite Fe3O4@AgNPs under a strong magnetic field, they outperformed the conventional silver nanoparticles during SERS measurements in terms of signal intensity, spot-to-spot, and sample-to-sample reproducibility. The SERS enhancement factor of Fe3O4@AgNP-adsorbed 4-mercaptobenzoic acid (4-MBA) was estimated to be 3.1 × 107 for a 633 nm excitation. In addition, we show that simply by changing the initial volumes of the colloid solutions, it is possible to control the average density of the silver nanoparticles, which are attached to a single magnetite nanoparticle. UV-Vis and SERS data revealed a possibility to tune the plasmonic resonance frequency of Fe3O4@AgNPs. In this research, the plasmon resonance maximum varied from 470 to 800 nm, suggesting the possibility to choose the most suitable nanoparticle composition for the particular SERS experiment design. We emphasize the increased thermal stability of composite nanoparticles under 532 and 442 nm laser light irradiation compared to that of bare Fe3O4 nanoparticles. The Fe3O4@AgNPs were further characterized by XRD, TEM, and magnetization measurements.

| S-EPMC9416134 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data