Ontology highlight
ABSTRACT:
SUBMITTER: Gomez-Acevedo H
PROVIDER: S-EPMC7039967 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Gomez-Acevedo Horacio H Dai Yuemeng Y Strub Graham G Shawber Carrie C Wu June K JK Richter Gresham T GT
Scientific reports 20200224 1
Infantile hemangiomas (IHs) are the most common benign tumors in early childhood. They show a distinctive mechanism of tumor growth in which a rapid proliferative phase is followed by a regression phase (involution). Propranolol is an approved treatment for IHs, but its mechanism of action remains unclear. We integrated and harmonized microRNA and mRNA transcriptome data from newly generated microarray data on IHs with publicly available data on toxicological transcriptomics from propranolol exp ...[more]