Ontology highlight
ABSTRACT:
SUBMITTER: Kaludercic N
PROVIDER: S-EPMC7040199 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Kaludercic Nina N Di Lisa Fabio F
Frontiers in cardiovascular medicine 20200218
Diabetic cardiomyopathy is a result of diabetes-induced changes in the structure and function of the heart. Hyperglycemia affects multiple pathways in the diabetic heart, but excessive reactive oxygen species (ROS) generation and oxidative stress represent common denominators associated with adverse tissue remodeling. Indeed, key processes underlying cardiac remodeling in diabetes are redox sensitive, including inflammation, organelle dysfunction, alteration in ion homeostasis, cardiomyocyte hyp ...[more]