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Role of Surgery in Clostridium difficile Infection.


ABSTRACT: Clostridium (reclassified as " Clostridioides ") difficile infection (CDI) occurs as a chronic or an acute illness with intensity varying from mild to severe. Although most cases of CDI can be managed with antibiotics and supportive care, when the patient presents with fulminant disease, the early decision to perform surgery is imperative for survival. The current standard of care is the subtotal colectomy. However, loop ileostomy with vancomycin enemas delivered into the colonic mucosa has been described as a viable option on selected patients.

SUBMITTER: Vely A 

PROVIDER: S-EPMC7042015 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Role of Surgery in <i>Clostridium difficile</i> Infection.

Vely Aela A   Ferrada Paula P  

Clinics in colon and rectal surgery 20200225 2


<i>Clostridium</i> (reclassified as " <i>Clostridioides</i> ") <i>difficile</i> infection (CDI) occurs as a chronic or an acute illness with intensity varying from mild to severe. Although most cases of CDI can be managed with antibiotics and supportive care, when the patient presents with fulminant disease, the early decision to perform surgery is imperative for survival. The current standard of care is the subtotal colectomy. However, loop ileostomy with vancomycin enemas delivered into the co  ...[more]

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