Ontology highlight
ABSTRACT:
SUBMITTER: Kalantri SA
PROVIDER: S-EPMC7042442 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 20190906 1
HbE Beta thalassemia is phenotypically very diverse disease. We aim to study role of various genetic factors in determining severity of this disease. 243 diagnosed cases of HbE Beta thalassemia were included in this study. Patients were divided in two arms-transfusion dependent and non-transfusion dependent arms. Various factors (percentage of haemoglobin F, hemoglobin E, type of Beta mutation, Xmn1 polymorphism, alpha deletion, HPFH mutation) were evaluated in these patients. Xmn1 polymorphism ...[more]