Ontology highlight
ABSTRACT:
SUBMITTER: van Dop M
PROVIDER: S-EPMC7042713 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
van Dop Maritza M Fiedler Marc M Mutte Sumanth S de Keijzer Jeroen J Olijslager Lisa L Albrecht Catherine C Liao Che-Yang CY Janson Marcel E ME Bienz Mariann M Weijers Dolf D
Cell 20200130 3
Cell polarity is fundamental for tissue morphogenesis in multicellular organisms. Plants and animals evolved multicellularity independently, and it is unknown whether their polarity systems are derived from a single-celled ancestor. Planar polarity in animals is conferred by Wnt signaling, an ancient signaling pathway transduced by Dishevelled, which assembles signalosomes by dynamic head-to-tail DIX domain polymerization. In contrast, polarity-determining pathways in plants are elusive. We rece ...[more]