Ontology highlight
ABSTRACT:
SUBMITTER: Pennisi M
PROVIDER: S-EPMC7042979 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Pennisi Martina M Jain Tania T Santomasso Bianca D BD Mead Elena E Wudhikarn Kitsada K Silverberg Mari Lynne ML Batlevi Yakup Y Shouval Roni R Devlin Sean M SM Batlevi Connie C Brentjens Renier J RJ Dahi Parastoo B PB Diamonte Claudia C Giralt Sergio S Halton Elizabeth F EF Maloy Molly M Palomba Maria Lia ML Sanchez-Escamilla Miriam M Sauter Craig S CS Scordo Michael M Shah Gunjan G Park Jae H JH Perales Miguel-Angel MA
Blood advances 20200201 4
Various grading systems are currently used for chimeric antigen receptor (CAR) T-cell-related toxicity, cytokine release syndrome (CRS), and immune effector cell-associated neurotoxicity syndrome (ICANS). We compared the recently proposed American Society for Transplantation and Cellular Therapy (ASTCT) grading system to other grading scores in 2 populations of adults: patients (n = 53) with B-cell acute lymphoblastic leukemia (B-ALL) treated with 1928z CAR T-cells (clinicaltrials.gov #NCT010440 ...[more]