The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression.
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ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC7045519 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression.
Wu Yuqing Y Zhang Siwei S Gong Xiaoxiao X Tam Samantha S Xiao Desheng D Liu Shuang S Tao Yongguang Y
Molecular cancer 20200227 1
Ferroptosis, a novel form of regulated cell death, is different from other types of cell death in morphology, genetics and biochemistry. Increasing evidence indicates that ferroptosis has significant implications on cell death linked to cardiomyopathy, tumorigenesis, and cerebral hemorrhage to name a few. Here we summarize current literature on ferroptosis, including organelle dysfunction, signaling transduction pathways, metabolic reprogramming and epigenetic regulators in cancer progression. W ...[more]
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