Ontology highlight
ABSTRACT:
SUBMITTER: Wan B
PROVIDER: S-EPMC7045884 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Wan Bangbei B Liu Bo B Lv Cai C
PeerJ 20200224
Circular RNAs (circRNAs) are a large class of endogenous RNA that form a covalently closed continuous loop without 5' or 3' tails and are diffusely expressed in mammalian cells. Through the development of high-throughput sequencing, microarray, and bioinformatics analyses, recent studies have shown that the expression of circRNAs is dysregulated in human tumor tissues and cells, as well as in the blood of patients, and closely correlates with the development of tumors. circRNAs can regulate the ...[more]