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Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis.


ABSTRACT: Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) filaggrin (FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No significant differences in the allele, genotype and haplotype frequencies between males and females with AD patients were observed.

SUBMITTER: Belyaeva T 

PROVIDER: S-EPMC7047013 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis.

Belyaeva Tatyana T   Ponomarenko Irina I   Reshetnikov Evgeny E   Polonikov Alexey A   Aristova Inna I   Elykova Anna A   Rudykh Natalya N   Churnosov Mikhail M  

Data in brief 20200221


Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) <i>filaggrin</i> (<i>FLG</i>) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No  ...[more]

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