Ontology highlight
ABSTRACT:
SUBMITTER: Boulestreau J
PROVIDER: S-EPMC7047768 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Boulestreau Jérémy J Maumus Marie M Rozier Pauline P Jorgensen Christian C Noël Danièle D
Frontiers in cell and developmental biology 20200221
Aging is associated with high prevalence of chronic degenerative diseases that take a large part of the increasing burden of morbidities in a growing demographic of elderly people. Aging is a complex process that involves cell autonomous and cell non-autonomous mechanisms where senescence plays an important role. Senescence is characterized by the loss of proliferative potential, resistance to cell death by apoptosis and expression of a senescence-associated secretory phenotype (SASP). SASP incl ...[more]