When Long Noncoding Becomes Protein Coding.
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ABSTRACT:
SUBMITTER: Hartford CCR
PROVIDER: S-EPMC7048269 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
When Long Noncoding Becomes Protein Coding.
Hartford Corrine Corrina R CCR Lal Ashish A
Molecular and cellular biology 20200227 6
Recent advancements in genetic and proteomic technologies have revealed that more of the genome encodes proteins than originally thought possible. Specifically, some putative long noncoding RNAs (lncRNAs) have been misannotated as noncoding. Numerous lncRNAs have been found to contain short open reading frames (sORFs) which have been overlooked because of their small size. Many of these sORFs encode small proteins or micropeptides with fundamental biological importance. These micropeptides can a ...[more]
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