Ontology highlight
ABSTRACT:
SUBMITTER: Johnson RK
PROVIDER: S-EPMC7048736 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Johnson Randi K RK Vanderlinden Lauren A LA Dong Fran F Carry Patrick M PM Seifert Jennifer J Waugh Kathleen K Shorrosh Hanan H Fingerlin Tasha T Frohnert Brigitte I BI Yang Ivana V IV Kechris Katerina K Rewers Marian M Norris Jill M JM
Scientific reports 20200228 1
DNA methylation may be involved in development of type 1 diabetes (T1D), but previous epigenome-wide association studies were conducted among cases with clinically diagnosed diabetes. Using multiple pre-disease peripheral blood samples on the Illumina 450 K and EPIC platforms, we investigated longitudinal methylation differences between 87 T1D cases and 87 controls from the prospective Diabetes Autoimmunity Study in the Young (DAISY) cohort. Change in methylation with age differed between cases ...[more]