Ontology highlight
ABSTRACT:
SUBMITTER: Rambousek L
PROVIDER: S-EPMC7048777 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Rambousek Lukas L Gschwind Tilo T Lafourcade Carlos C Paterna Jean-Charles JC Dib Linda L Fritschy Jean-Marc JM Fontana Adriano A
Scientific reports 20200228 1
Epilepsy is a widespread neurological disease characterized by abnormal neuronal activity resulting in recurrent seizures. There is mounting evidence that a circadian system disruption, involving clock genes and their downstream transcriptional regulators, is associated with epilepsy. In this study, we characterized the hippocampal expression of clock genes and PAR bZIP transcription factors (TFs) in a mouse model of temporal lobe epilepsy induced by intrahippocampal injection of kainic acid (KA ...[more]