Dataset Information

Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults.

ABSTRACT: Background:In China, lack of evidence remains a significant challenge for the national initiative to promote physical activity (PA). We aimed to quantify the beneficial effects of meeting or maintaining the recommended PA level [150 minutes per week (min/wk) of moderate PA or 75 min/wk of vigorous PA or an equivalent combination] on incident cardiovascular disease (CVD) among Chinese population. Methods:We included 100,560 participants without history of CVD from three cohorts in the Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR) project. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for CVD events and its subtypes, including stroke, coronary heart disease, heart failure, and CVD death. Results:During a median follow-up of 7.3 years (range: 6-15 years), 777,163 person-years and 4693 incident CVD events were observed. Compared with participants who were inactive at baseline, the multivariable adjusted HR (95% CI) of developing CVD was 0.74 (0.69-0.79) for those who met recommended moderate to vigorous physical activity (MVPA) level at baseline. Furthermore, the risk of CVD incidence was reduced with increment of MVPA (P trend < 0.001), and the HR (95% CI) of highly-active versus inactive category was 0.62 (0.56-0.68). Compared with individuals who were inactive both at the baseline and follow-up, those keeping active over the period of follow-up had a substantial lower risk of incident CVD with the HR (95% CI) of 0.57 (0.43-0.77). Conclusions:The findings demonstrated that meeting and maintaining the recommended MVPA level could reduce the cardiovascular risk. Wider adoption of the PA recommendations would have considerable health impacts to the Chinese population.

SUBMITTER: Liu Q

PROVIDER: S-EPMC7051870 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults.

Liu Qiong Q Liu Fang-Chao FC Huang Ke-Yong KY Li Jian-Xin JX Yang Xue-Li XL Wang Xin-Yan XY Chen Ji-Chun JC Liu Xiao-Qing XQ Cao Jie J Shen Chong C Yu Ling L Lu Fang-Hong FH Wu Xian-Ping XP Zhao Lian-Cheng LC Li Ying Y Hu Dong-Sheng DS Lu Xiang-Feng XF Huang Jian-Feng JF Gu Dong-Feng DF

Journal of geriatric cardiology : JGC 20200201 2

<h4>Background</h4>In China, lack of evidence remains a significant challenge for the national initiative to promote physical activity (PA). We aimed to quantify the beneficial effects of meeting or maintaining the recommended PA level [150 minutes per week (min/wk) of moderate PA or 75 min/wk of vigorous PA or an equivalent combination] on incident cardiovascular disease (CVD) among Chinese population.<h4>Methods</h4>We included 100,560 participants without history of CVD from three cohorts in ...[more]

PMID: 32165881

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Project description:The positive association between the total duration of physical activity and performances of physical function may vary at different times of the day as circadian rhythm regulates individuals in response to external stimulations. We aimed to examine the association of timing-specific and overall moderate-to-vigorous physical activity (MVPA) with performances of physical function in older adults. A cross-sectional analysis was conducted among 118 older adults (mean age?=?70.0?±?5.0 years). We assessed and identified timing-specific (morning: 06:01-12:00; afternoon: 12:01-18:00; evening: 18:01-24:00) and overall MVPA using a triaxial accelerometer. Different measures of physical function were evaluated including handgrip strength (by grip dynamometer), gait speed (5-m walk test), basic functional mobility (timed up and go test), and lower limb strength (five times sit-to-stand test). Multivariate linear regression models adjusting for covariates were used to investigate the associations. Participants spent 25.0 (±?26.2) minutes in MVPA per day on average, half the time spent during the morning (47.7%), followed by during the afternoon (29.9%) and evening (21.6%). The time spent on overall MVPA was generally associated with better physical function performances. There was statistical evidence for the percentages of MVPA engagement during the morning [B?=?0.214, 95% confidence interval (CI) 0.001 to 0.428] and afternoon (B?=?-?0.273, 95% CI -?0.518 to -?0.027) associated with basic functional mobility but with contrary directions; the percentage of MVPA engagement during the evening was associated with less time spent in gait speed performance (B?=?-?0.237, 95% CI -?0.468 to -?0.006). Our findings inform implications that the overall MVPA engagement was more important than timing-specific MVPA to older adults' physical function performances. Strategies for accumulating time of MVPA is more practical and effective than encouraging to engage MVPA in specific timing for the enhancement of functional ability and therefore prevent disability among older adults.

Dataset Information

Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults.

Publications

Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults.

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