Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health.
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ABSTRACT:
SUBMITTER: Parker A
PROVIDER: S-EPMC7053956 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health.
Parker Aimée A Fonseca Sonia S Carding Simon R SR
Gut microbes 20190801 2
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with the host. When intestinal homeostasis is perturbed, the function of the gastrointestinal tract and other organ systems, including the brain, can be compromised. The gut microbiota is proposed to contribute to blood-brain barrier disruption and the pathogenesis of neurodegenerative diseases. While progress is being ...[more]
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