Ontology highlight
ABSTRACT:
SUBMITTER: Yi SW
PROVIDER: S-EPMC7054540 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Yi Sang-Wook SW Kim Se Hwa SH Han Ki Jun KJ Yi Jee-Jeon JJ Ohrr Heechoul H
British journal of cancer 20191220 5
We aimed to examine whether statin users have a lower risk of hepatocellular carcinoma (HCC) after careful consideration of prevalent statin use and cholesterol levels. During a mean prospective follow-up of 8.4 years in 400,318 Koreans, 1686 individuals were diagnosed with HCC. When prevalent users were included, HCC risk was reduced by >50% in statin users, regardless of adjustment for total cholesterol (TC). When prevalent users were excluded, new users who initiated statins within 6 months a ...[more]