Ontology highlight
ABSTRACT:
SUBMITTER: Tsai YC
PROVIDER: S-EPMC7054723 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Tsai Yi-Chun YC Kuo Mei-Chuan MC Hung Wei-Wen WW Wu Ling-Yu LY Wu Ping-Hsun PH Chang Wei-An WA Kuo Po-Lin PL Hsu Ya-Ling YL
Molecular therapy : the journal of the American Society of Gene Therapy 20200115 3
Diabetic nephropathy (DN) is an increasing threat to human health and is regarded as an important public issue. The pathophysiologic mechanisms of DN are complicated. The initiating molecular events triggering the loss function in mesangial cells (MCs) in DN are not well known. In this cross-disciplinary study, transcriptome analysis of high glucose (HG)-treated mouse MCs (MMCs) using next-generation sequencing and systematic bioinformatics analyses indicated that miR-15b-5p and its downstream t ...[more]