Dataset Information

Longitudinal spatial dataset on travel times and distances by different travel modes in Helsinki Region.

ABSTRACT: Comparable data on spatial accessibility by different travel modes are frequently needed to understand how city regions function. Here, we present a spatial dataset called the Helsinki Region Travel Time Matrix that has been calculated for 2013, 2015 and 2018. This longitudinal dataset contains travel time and distance information between all 250?metres statistical grid cell centroids in the Capital Region of Helsinki, Finland. The dataset is multimodal and multitemporal by nature: all typical transport modes (walking, cycling, public transport, and private car) are included and calculated separately for the morning rush hour and midday for an average working day. We followed a so-called door-to-door principle, making the information between travel modes comparable. The analyses were based primarily on open data sources, and all the tools that were used to produce the data are openly available. The matrices form a time-series that can reveal the accessibility conditions within the city and allow comparisons of the changes in accessibility in the region, which support spatial planning and decision-making.

SUBMITTER: Tenkanen H

PROVIDER: S-EPMC7055230 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Longitudinal spatial dataset on travel times and distances by different travel modes in Helsinki Region.

Tenkanen Henrikki H Toivonen Tuuli T

Scientific data 20200304 1

Comparable data on spatial accessibility by different travel modes are frequently needed to understand how city regions function. Here, we present a spatial dataset called the Helsinki Region Travel Time Matrix that has been calculated for 2013, 2015 and 2018. This longitudinal dataset contains travel time and distance information between all 250 metres statistical grid cell centroids in the Capital Region of Helsinki, Finland. The dataset is multimodal and multitemporal by nature: all typical t ...[more]

PMID: 32132539

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Project description:Empirical observations and theoretical studies suggest that viruses may use different replication strategies to amplify their genomes, which impact the dynamics of mutation accumulation in viral populations and therefore, their fitness and virulence. Similarly, during natural infections, viruses replicate and infect cells that are rarely in suspension but spatially organized. Surprisingly, most quasispecies models of virus replication have ignored these two phenomena. In order to study these two viral characteristics, we have developed stochastic cellular automata models that simulate two different modes of replication (geometric vs stamping machine) for quasispecies replicating and spreading on a two-dimensional space. Furthermore, we explored these two replication models considering epistatic fitness landscapes (antagonistic vs synergistic) and different scenarios for cell-to-cell spread, one with free superinfection and another with superinfection inhibition. We found that the master sequences for populations replicating geometrically and with antagonistic fitness effects vanished at low critical mutation rates. By contrast, the highest critical mutation rate was observed for populations replicating geometrically but with a synergistic fitness landscape. Our simulations also showed that for stamping machine replication and antagonistic epistasis, a combination that appears to be common among plant viruses, populations further increased their robustness by inhibiting superinfection. We have also shown that the mode of replication strongly influenced the linkage between viral loci, which rapidly reached linkage equilibrium at increasing mutations for geometric replication. We also found that the strategy that minimized the time required to spread over the whole space was the stamping machine with antagonistic epistasis among mutations. Finally, our simulations revealed that the multiplicity of infection fluctuated but generically increased along time.

Dataset Information

Longitudinal spatial dataset on travel times and distances by different travel modes in Helsinki Region.

Publications

Longitudinal spatial dataset on travel times and distances by different travel modes in Helsinki Region.

Similar Datasets

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