Ontology highlight
ABSTRACT:
SUBMITTER: de Miguel Perez D
PROVIDER: S-EPMC7055306 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
de Miguel Pérez Diego D Rodriguez Martínez Alba A Ortigosa Palomo Alba A Delgado Ureña Mayte M Garcia Puche Jose Luis JL Robles Remacho Agustín A Exposito Hernandez José J Lorente Acosta Jose Antonio JA Ortega Sánchez Francisco Gabriel FG Serrano Ma Jose MJ
Scientific reports 20200304 1
Disseminated disease is present in ≈50% of colorectal cancer patients upon diagnosis, being responsible for most of cancer deaths. Addition of biological drugs, as Bevacizumab, to chemotherapy, has increased progression free survival and overall survival of metastatic colorectal cancer (mCRC) patients. However, these benefits have been only reported in a small proportion of patients. To date, there are not biomarkers that could explain the heterogeneity of this disease and would help in treatmen ...[more]