Unknown

Dataset Information

0

A MAPP Network Case-control Study of Urological Chronic Pelvic Pain Compared With Nonurological Pain Conditions.


ABSTRACT:

Objectives

Limited research suggests commonalities between urological chronic pelvic pain syndromes (UCPPS) and other nonurological chronic overlapping pain conditions (COPCs) including fibromyalgia, chronic fatigue syndrome, and irritable bowel syndrome. The goal of this case-control study was to examine similarities and differences between UCPPS and these other COPCs.

Materials and methods

As part of the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research (MAPP) Network, we examined 1039 individuals with UCPPS (n=424), nonurological COPCs (n=200), and healthy controls (HCs; n=415). Validated standardized measures were used to assess urological symptoms, nonurological pain symptoms, and psychosocial symptoms and traits.

Results

Participants with UCPPS had more urological symptoms than nonurological COPCs or HCs (P<0.001); nonurological COPC group also had significantly worse urological symptoms than HCs (P<0.001). Participants with nonurological COPCs reported more widespread pain than those with UCPPS (P<0.001), yet both groups had similarly increased symptoms of anxiety, depression, negative affect, perceived stress, neuroticism, and lower levels of extraversion than HCs (P<0.001). Participants with UCPPS with and without COPCs reported more catastrophizing than those with nonurological COPCs (P<0.001).

Discussion

Findings are consistent with the hypothesis of common underlying biopsychosocial mechanisms and can guide the comprehensive assessment and treatment of these conditions regardless of the primary site of pain or diagnosis. Heightened catastrophizing in UCPPS should be examined to inform psychosocial interventions and improve patient care.

SUBMITTER: Afari N 

PROVIDER: S-EPMC7055954 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

A MAPP Network Case-control Study of Urological Chronic Pelvic Pain Compared With Nonurological Pain Conditions.

Afari Niloofar N   Buchwald Dedra D   Clauw Daniel D   Hong Barry B   Hou Xiaoling X   Krieger John N JN   Mullins Chris C   Stephens-Shields Alisa J AJ   Gasperi Marianna M   Williams David A DA  

The Clinical journal of pain 20190926 1


<h4>Objectives</h4>Limited research suggests commonalities between urological chronic pelvic pain syndromes (UCPPS) and other nonurological chronic overlapping pain conditions (COPCs) including fibromyalgia, chronic fatigue syndrome, and irritable bowel syndrome. The goal of this case-control study was to examine similarities and differences between UCPPS and these other COPCs.<h4>Materials and methods</h4>As part of the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research (MA  ...[more]

Similar Datasets

| S-EPMC5911194 | biostudies-literature
| S-EPMC5117992 | biostudies-literature
| S-EPMC5562525 | biostudies-literature
| S-EPMC9179931 | biostudies-literature
| S-EPMC6800057 | biostudies-literature
| S-EPMC5720154 | biostudies-literature
| S-EPMC8139408 | biostudies-literature
| S-EPMC4134515 | biostudies-literature
| S-EPMC4669971 | biostudies-literature
| S-EPMC4497586 | biostudies-literature