Ontology highlight
ABSTRACT:
SUBMITTER: Podyma B
PROVIDER: S-EPMC7056271 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Podyma Brandon B Johnson Dove-Anna DA Sipe Laura L Remcho Thomas Parks TP Battin Katherine K Liu Yuxi Y Yoon Sung Ok SO Deppmann Christopher D CD Güler Ali Deniz AD
eLife 20200129
Networks of neurons control feeding and activity patterns by integrating internal metabolic signals of energy balance with external environmental cues such as time-of-day. Proper circadian alignment of feeding behavior is necessary to prevent metabolic disease, and thus it is imperative that molecular players that maintain neuronal coordination of energy homeostasis are identified. Here, we demonstrate that mice lacking the p75 neurotrophin receptor, p75NTR, decrease their feeding and food antic ...[more]