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Induction of membrane curvature by proteins involved in Golgi trafficking.

ABSTRACT: The Golgi apparatus serves a key role in processing and sorting lipids and proteins for delivery to their final cellular destinations. Vesicle exit from the Golgi initiates with directional deformation of the lipid bilayer to produce a bulge. Several mechanisms have been described by which lipids and proteins can induce directional membrane curvature to promote vesicle budding. Here we review some of the mechanisms implicated in inducing membrane curvature at the Golgi to promote vesicular trafficking to various cellular destinations.

SUBMITTER: Makowski SL

PROVIDER: S-EPMC7056495 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Induction of membrane curvature by proteins involved in Golgi trafficking.

Makowski Stefanie L SL Kuna Ramya S RS Field Seth J SJ

Advances in biological regulation 20191016

The Golgi apparatus serves a key role in processing and sorting lipids and proteins for delivery to their final cellular destinations. Vesicle exit from the Golgi initiates with directional deformation of the lipid bilayer to produce a bulge. Several mechanisms have been described by which lipids and proteins can induce directional membrane curvature to promote vesicle budding. Here we review some of the mechanisms implicated in inducing membrane curvature at the Golgi to promote vesicular traff ...[more]

PMID: 31668661

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