Selective Sweeps Under Dominance and Inbreeding.
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ABSTRACT:
SUBMITTER: Hartfield M
PROVIDER: S-EPMC7056974 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Publications
Selective Sweeps Under Dominance and Inbreeding.
Hartfield Matthew M Bataillon Thomas T
G3 (Bethesda, Md.) 20200305 3
A major research goal in evolutionary genetics is to uncover loci experiencing positive selection. One approach involves finding 'selective sweeps' patterns, which can either be 'hard sweeps' formed by <i>de novo</i> mutation, or 'soft sweeps' arising from recurrent mutation or existing standing variation. Existing theory generally assumes outcrossing populations, and it is unclear how dominance affects soft sweeps. We consider how arbitrary dominance and inbreeding via self-fertilization affect ...[more]
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