Particulate Matter and Albuminuria, Glomerular Filtration Rate, and Incident CKD.

ABSTRACT:

Background and objectives

Exposure to particulate matter (PM) <2.5 μm in aerodynamic diameter (PM_2.5) has been linked to detrimental health effects. This study aimed to describe the relationship between long-term PM_2.5 exposure and kidney disease, including eGFR, level of albuminuria, and incident CKD.

Design, setting, participants, & measurements

The study included 10,997 participants from the Atherosclerosis Risk in Communities cohort who were followed from 1996-1998 through 2016. Monthly mean PM_2.5 concentrations (μg/m³) were estimated at geocoded participant addresses using geographic information system-based, spatiotemporal generalized additive mixed models-including geospatial covariates such as land use-and the

SUBMITTER: Blum MF 

PROVIDER: S-EPMC7057299 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature