Survival after Kidney Transplantation during Childhood and Adolescence.

ABSTRACT:

Background and objectives

Survival in pediatric kidney transplant recipients has improved over the past five decades, but changes in cause-specific mortality remain uncertain. The aim of this retrospective cohort study was to estimate the associations between transplant era and overall and cause-specific mortality for child and adolescent recipients of kidney transplants.

Design, setting, participants, & measurements

Data were obtained on all children and adolescents (aged <20 years) who received their first kidney transplant from 1970 to 2015 from the Australian and New Zealand Dialysis and Transplant Registry. Mortality rates were compared across eras using Cox regression, adjusted for confounders.

Results

A total of 1810 recipients (median age at transplantation 14

SUBMITTER: Francis A 

PROVIDER: S-EPMC7057311 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature