Unknown

Dataset Information

0

Phosphine-Free Ru-Catalyzed Regio- and Stereoselective Addition of Benzoic Acids to Trifluoromethylated Alkynes toward Facile Access to Trifluoromethyl Group-Substituted (E)-Enol Esters.

ABSTRACT: A combination of ruthenium catalyst with silver salt and copper salt was proved to be a highly efficient protocol for the direct addition reaction of benzoic acids with unsymmetrical trifluoromethylated internal alkynes. Diverse trifluoromethyl group-substituted (E)-enol esters were readily obtained for a broad substrate scope in moderate to good yields with excellent regio- and stereoselectivities under mild reaction conditions.

SUBMITTER: Liu G 

PROVIDER: S-EPMC7057715 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Phosphine-Free Ru-Catalyzed Regio- and Stereoselective Addition of Benzoic Acids to Trifluoromethylated Alkynes toward Facile Access to Trifluoromethyl Group-Substituted (<i>E</i>)-Enol Esters.

Liu Guangyuan G   Zhang Xingxing X   Kuang Guanghua G   Lu Naihao N   Fu Yang Y   Peng Yiyuan Y   Xiao Qiang Q   Zhou Yirong Y  

ACS omega 20200220 8

A combination of ruthenium catalyst with silver salt and copper salt was proved to be a highly efficient protocol for the direct addition reaction of benzoic acids with unsymmetrical trifluoromethylated internal alkynes. Diverse trifluoromethyl group-substituted (<i>E</i>)-enol esters were readily obtained for a broad substrate scope in moderate to good yields with excellent regio- and stereoselectivities under mild reaction conditions. ...[more]

Similar Datasets

Unknown Scope and Mechanistic Investigations on the Solvent-Controlled Regio- and Stereoselective Formation of Enol Esters from the Ruthenium-Catalyzed Coupling Reaction of Terminal Alkynes and Carboxylic Acids.
| S-EPMC2782529 | biostudies-literature
Unknown Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates.
| S-EPMC5460293 | biostudies-literature
Unknown Highly Efficient Gold(I)-Catalyzed Regio- and Stereoselective Hydrocarboxylation of Internal Alkynes.
| S-EPMC5745071 | biostudies-literature
Unknown Highly regio- and stereoselective phosphinylphosphination of terminal alkynes with tetraphenyldiphosphine monoxide under radical conditions.
| S-EPMC8077611 | biostudies-literature
Unknown Trifluoromethyl Nonaflate: A Practical Trifluoromethoxylating Reagent and its Application to the Regio- and Stereoselective Synthesis of Trifluoromethoxylated Alkenes.
| S-EPMC8260458 | biostudies-literature
Unknown Stereoselective Syntheses of ?,?-Unsaturated ?-Amino Esters Through Phosphine-Catalyzed ?-Umpolung Additions of Sulfonamides to ?-Substituted Allenoates.
| S-EPMC4450090 | biostudies-literature
Unknown Regio- and Stereoselective Homologation of 1,2-Bis(Boronic Esters): Stereocontrolled Synthesis of 1,3-Diols and Sch?725674.
| S-EPMC5129522 | biostudies-literature
Unknown Stereoselective cobalt-catalyzed halofluoroalkylation of alkynes.
| S-EPMC5892352 | biostudies-other
Unknown Regio- and Stereoselective Allylindation of Alkynes Using InBr? and Allylic Silanes: Synthesis, Characterization, and Application of 1,4-Dienylindiums toward Skipped Dienes.
| S-EPMC6222668 | biostudies-literature
Unknown Regio- and Stereoselective Synthesis of 1,1-Diborylalkenes via Bronsted Base-Catalyzed Mixed Diboration of Alkynyl Esters and Amides with BpinBdan.
| S-EPMC7187442 | biostudies-literature