Ontology highlight
ABSTRACT:
SUBMITTER: Roark HK
PROVIDER: S-EPMC7057791 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Roark Hunter K HK Jenks Jennifer A JA Permar Sallie R SR Schleiss Mark R MR
The Journal of infectious diseases 20200301 Suppl 1
Although cytomegaloviruses (CMVs) are species-specific, the study of nonhuman CMVs in animal models can help to inform and direct research aimed at developing a human CMV (HCMV) vaccine. Because the driving force behind the development of HCMV vaccines is to prevent congenital infection, the animal model in question must be one in which vertical transmission of virus occurs to the fetus. Fortunately, two such animal models-the rhesus macaque CMV and guinea pig CMV-are characterized by congenital ...[more]