Ontology highlight
ABSTRACT:
SUBMITTER: Kim HJ
PROVIDER: S-EPMC7057842 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Kim Hyun-Jung HJ Kim Woo-Jin WJ Ryoo Hyun-Mo HM
Molecules and cells 20200201 2
Runt-related transcription factor 2 (RUNX2) is a key transcription factor for bone formation and osteoblast differentiation. Various signaling pathways and mechanisms that regulate the expression and transcriptional activity of RUNX2 have been thoroughly investigated since the involvement of RUNX2 was first reported in bone formation. As the regulation of Runx2 expression by extracellular signals has recently been reviewed, this review focuses on the regulation of post-translational RUNX2 activi ...[more]