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Immunomodulation for maxillofacial reconstructive surgery.


ABSTRACT: Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings.

SUBMITTER: Kim SG 

PROVIDER: S-EPMC7058765 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Immunomodulation for maxillofacial reconstructive surgery.

Kim Seong-Gon SG  

Maxillofacial plastic and reconstructive surgery 20200305 1


Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone gra  ...[more]

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