Unknown

Dataset Information

0

A LuxR-type regulator, AcrR, regulates flagellar assembly and contributes to virulence, motility, biofilm formation, and growth ability of Acidovorax citrulli.


ABSTRACT: LuxR-type regulators regulate many bacterial processes and play important roles in bacterial motility and virulence. Acidovorax citrulli is a seedborne bacterial pathogen responsible for bacterial fruit blotch, which causes great losses in melon and watermelon worldwide. We identified a LuxR-type, nonquorum sensing-related regulator, AcrR, in the group II strain Aac-5 of A. citrulli. We found that the acrR mutant lost twitching and swimming motilities, and flagellar formation. It also showed reduced virulence, but increased biofilm formation and growth ability. Transcriptomic analysis revealed that 394 genes were differentially expressed in the acrR mutant of A. citrulli, including 33 genes involved in flagellar assembly. Our results suggest that AcrR may act as a global regulator affecting multiple important biological functions of A. citrulli.

SUBMITTER: Guan W 

PROVIDER: S-EPMC7060138 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

altmetric image

Publications

A LuxR-type regulator, AcrR, regulates flagellar assembly and contributes to virulence, motility, biofilm formation, and growth ability of Acidovorax citrulli.

Guan Wei W   Wang Tielin T   Huang Qi Q   Tian Eryuan E   Liu Bo B   Yang Yuwen Y   Zhao Tingchang T  

Molecular plant pathology 20200114 4


LuxR-type regulators regulate many bacterial processes and play important roles in bacterial motility and virulence. Acidovorax citrulli is a seedborne bacterial pathogen responsible for bacterial fruit blotch, which causes great losses in melon and watermelon worldwide. We identified a LuxR-type, nonquorum sensing-related regulator, AcrR, in the group II strain Aac-5 of A. citrulli. We found that the acrR mutant lost twitching and swimming motilities, and flagellar formation. It also showed red  ...[more]

Similar Datasets

| S-EPMC6638315 | biostudies-literature
| S-EPMC7546022 | biostudies-literature
| S-EPMC4691024 | biostudies-literature
| S-EPMC3429658 | biostudies-literature
| S-EPMC10052978 | biostudies-literature
| S-EPMC3759439 | biostudies-literature
| S-EPMC3438124 | biostudies-literature
| S-EPMC7798450 | biostudies-literature
| S-EPMC8851203 | biostudies-literature
| S-EPMC7509047 | biostudies-literature