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Re-resection in Incidental Gallbladder Cancer: Survival and the Incidence of Residual Disease.

ABSTRACT: BACKGROUND:Re-resection for incidental gallbladder cancer (iGBC) is associated with improved survival but little is known about residual disease (RD) and prognostic factors. In this study, survival after re-resection, RD, and prognostic factors are analyzed. METHODS:Patients with iGBC were identified from the Netherlands Cancer Registry, and pathology reports of re-resected patients were reviewed. Survival and prognostic factors were analyzed. RESULTS:Overall, 463 patients were included; 24% (n?=?110) underwent re-resection after a median interval of 66 days. RD was present in 35% of patients and was most frequently found in the lymph nodes (23%). R0 resection was achieved in 93 patients (92%). Median overall survival (OS) of patients without re-resection was 13.7 (95% confidence interval [CI] 11.6-15.6), compared with 52.6 months (95% CI 36.3-68.8) in re-resected patients (p?

SUBMITTER: de Savornin Lohman EAJ 

PROVIDER: S-EPMC7060151 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Re-resection in Incidental Gallbladder Cancer: Survival and the Incidence of Residual Disease.

de Savornin Lohman Elise A J EAJ   van der Geest Lydia G LG   de Bitter Tessa J J TJJ   Nagtegaal Iris D ID   van Laarhoven Cornelis J H M CJHM   van den Boezem Peter P   van der Post Chella S CS   de Reuver Philip R PR  

Annals of surgical oncology 20191118 4

<h4>Background</h4>Re-resection for incidental gallbladder cancer (iGBC) is associated with improved survival but little is known about residual disease (RD) and prognostic factors. In this study, survival after re-resection, RD, and prognostic factors are analyzed.<h4>Methods</h4>Patients with iGBC were identified from the Netherlands Cancer Registry, and pathology reports of re-resected patients were reviewed. Survival and prognostic factors were analyzed.<h4>Results</h4>Overall, 463 patients  ...[more]

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