A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being.
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ABSTRACT:
SUBMITTER: Michael DR
PROVIDER: S-EPMC7060206 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
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A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being.
Michael D R DR Jack A A AA Masetti G G Davies T S TS Loxley K E KE Kerry-Smith J J Plummer J F JF Marchesi J R JR Mullish B H BH McDonald J A K JAK Hughes T R TR Wang D D Garaiova I I Paduchová Z Z Muchová J J Good M A MA Plummer S F SF
Scientific reports 20200306 1
In an exploratory, block-randomised, parallel, double-blind, single-centre, placebo-controlled superiority study (ISRCTN12562026, funded by Cultech Ltd), 220 Bulgarian participants (30 to 65 years old) with BMI 25-34.9 kg/m<sup>2</sup> received Lab4P probiotic (50 billion/day) or a matched placebo for 6 months. Participants maintained their normal diet and lifestyle. Primary outcomes were changes in body weight, BMI, waist circumference (WC), waist-to-height ratio (WtHR), blood pressure and plas ...[more]
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