Ontology highlight
ABSTRACT:
SUBMITTER: Shah NP
PROVIDER: S-EPMC7062463 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Shah Nishal P NP Brackbill Nora N Rhoades Colleen C Kling Alexandra A Goetz Georges G Litke Alan M AM Sher Alexander A Simoncelli Eero P EP Chichilnisky E J EJ
eLife 20200309
Responses of sensory neurons are often modeled using a weighted combination of rectified linear subunits. Since these subunits often cannot be measured directly, a flexible method is needed to infer their properties from the responses of downstream neurons. We present a method for maximum likelihood estimation of subunits by soft-clustering spike-triggered stimuli, and demonstrate its effectiveness in visual neurons. For parasol retinal ganglion cells in macaque retina, estimated subunits partit ...[more]