Ontology highlight
ABSTRACT:
SUBMITTER: Blackwell JM
PROVIDER: S-EPMC7062464 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Blackwell Jennifer M JM Lesicko Alexandria Mh AM Rao Winnie W De Biasi Mariella M Geffen Maria N MN
eLife 20200131
The extensive feedback from the auditory cortex (AC) to the inferior colliculus (IC) supports critical aspects of auditory behavior but has not been extensively characterized. Previous studies demonstrated that activity in IC is altered by focal electrical stimulation and pharmacological inactivation of AC, but these methods lack the ability to selectively manipulate projection neurons. We measured the effects of selective optogenetic modulation of cortico-collicular feedback projections on IC s ...[more]