Therapeutic Use of Vitamin C in Cancer: Physiological Considerations.
Ontology highlight
ABSTRACT:
SUBMITTER: Roa FJ
PROVIDER: S-EPMC7063061 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Therapeutic Use of Vitamin C in Cancer: Physiological Considerations.
Roa Francisco J FJ Peña Eduardo E Gatica Marcell M Escobar-Acuña Kathleen K Saavedra Paulina P Maldonado Mafalda M Cuevas Magdalena E ME Moraga-Cid Gustavo G Rivas Coralia I CI Muñoz-Montesino Carola C
Frontiers in pharmacology 20200303
Since the early studies of William J. McCormick in the 1950s, vitamin C has been proposed as a candidate for the treatment of cancer. A number of reports have shown that pharmacological concentrations of vitamin C selectively kill cancer cells <i>in vitro</i> and decrease the growth rates of a number of human tumor xenografts in immunodeficient mice. However, up to the date there is still doubt regarding this possible therapeutic role of vitamin C in cancer, mainly because high dose administrati ...[more]
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