Ontology highlight
ABSTRACT:
SUBMITTER: Tang W
PROVIDER: S-EPMC7063483 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Tang Wei W Wang Di D Shao Lianqi L Liu Xiaobai X Zheng Jian J Xue Yixue Y Ruan Xuelei X Yang Chunqing C Liu Libo L Ma Jun J Li Zhen Z Liu Yunhui Y
Molecular therapy. Nucleic acids 20191116
Glioblastomas are the most common and malignant intracranial tumors with a low survival rate. Dysregulation of long non-coding RNAs and RNA-binding protein causes various diseases, including cancers. However, the function of LINC00680 and TTN-AS1 in the progression of glioblastomas is still elusive. In this study, we detected that LINC00680 and TTN-AS1 were upregulated in glioblastoma cells. RNA-binding protein EIF4A3 could prolong the half-life of LINC00680 and TTN-AS1. Knockdown of EIF4A3, LIN ...[more]